Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982736 | 0.79 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2TLR4 | |
| SCHEMBL13983157 | 0.77 | MAPT (0.48) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL13982703 | 0.76 | SMN1; SMN2 (0.46) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL13982735 | 0.75 | SMN1; SMN2 (0.45) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL30462497 | 0.75 | TDP1 (0.53) | MAPTKMT2AMAPK1MEN1ALDH1A1 | |
| SCHEMBL15987733 | 0.75 | TDP1 (0.53) | MAPTKMT2AMAPK1MEN1ALDH1A1 | |
| SCHEMBL13656495 | 0.75 | HRH2 (0.57) | MAPTNPC1RAB9AHRH3KMT2A | |
| SCHEMBL28853175 | 0.75 | MAPT (0.60) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9513657 | 0.75 | MAPT (0.56) | MAPTNPC1RAB9AKMT2ATLR4 | |
| SCHEMBL13982826 | 0.74 | GPR35 (0.48) | MAPTKMT2AMAPK1MEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156656-A2 | METHOD FOR MAKING BIARYL COMPOUNDS, COMPOUNDS MADE BY THE METHOD, AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |