Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20418095 | 0.79 | HTR2A (0.46) | TNKS2PBRM1HTR2ANOS2KMT2A | |
| SCHEMBL23260314 | 0.68 | — | — | |
| SCHEMBL4914352 | 0.66 | HSD17B10 (0.51) | TNKS2PBRM1HTR2AKMT2AKDM4E | |
| SCHEMBL1567417 | 0.66 | HTR2A (0.40) | TNKS2PBRM1HTR2AKDM4EALDH1A1 | |
| SCHEMBL28949190 | 0.64 | POLB (0.34) | TNKS2PBRM1HTR2ANOS2ALDH1A1 | |
| SCHEMBL19156718 | 0.63 | MEN1 (0.38) | TNKS2PBRM1HTR2AKMT2AMEN1 | |
| SCHEMBL29945705 | 0.62 | GPR3 (0.50) | TNKS2PBRM1HTR2AGPR3GAA | |
| SCHEMBL8416742 | 0.62 | GPR3 (0.50) | TNKS2PBRM1HTR2AGPR3GAA | |
| SCHEMBL21626118 | 0.61 | TSHR (0.40) | HTR2AKMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8414162 | 0.61 | GPR3 (0.39) | HTR2AKMT2AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156879-A1 | BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS | UNIVERSAL DISPLAY CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2007095118-A2 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | UNIVERSAL DISPLAY CORPORATION (US) | 2007-08-23 | — | — | WO | disclosed |
| US-20070190359-A1 | Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof | UNIVERSAL DISPLAY CORPORATION | 2007-08-16 | — | — | US | disclosed |
| US-20070190359-A1 | Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof | UNIVERSAL DISPLAY CORPORATION | 2007-08-16 | — | — | US | disclosed |