Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP8 | P22894 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13245282 | 1.00 | MMP13 (0.44) | MMP13MMP2MMP8MMP9KDM4E | |
| SCHEMBL13245313 | 0.94 | MMP13 (0.47) | MMP13MMP2MMP8MMP9KDM4E | |
| SCHEMBL13245276 | 0.93 | MMP13 (0.47) | MMP13MMP2MMP8MMP9KDM4E | |
| SCHEMBL13244967 | 0.91 | MMP13 (0.51) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL18712229 | 0.91 | MMP13 (0.51) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL13267514 | 0.90 | KDM4E (0.48) | KDM4E | |
| SCHEMBL3018972 | 0.84 | MMP13 (0.56) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL3018980 | 0.84 | MMP13 (0.56) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL18023396 | 0.83 | MMP13 (0.44) | MMP13MMP2MMP8MMP9KDM4E | |
| SCHEMBL3007908 | 0.83 | MMP13 (0.55) | MMP13MMP2MMP8MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |
| WO-2008154642-A2 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2008-12-18 | — | — | WO | disclosed |