Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP8 | P22894 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13984728 | 1.00 | MMP13 (0.44) | MMP13MMP2MMP8MMP9KDM4E | |
| SCHEMBL13245313 | 0.94 | MMP13 (0.47) | MMP13MMP2MMP8MMP9KDM4E | |
| SCHEMBL13245276 | 0.93 | MMP13 (0.47) | MMP13MMP2MMP8MMP9KDM4E | |
| SCHEMBL13244967 | 0.91 | MMP13 (0.51) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL18712229 | 0.91 | MMP13 (0.51) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL13267514 | 0.90 | KDM4E (0.48) | KDM4E | |
| SCHEMBL3018972 | 0.84 | MMP13 (0.56) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL3018980 | 0.84 | MMP13 (0.56) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL18023396 | 0.83 | MMP13 (0.44) | MMP13MMP2MMP8MMP9KDM4E | |
| SCHEMBL3007908 | 0.83 | MMP13 (0.55) | MMP13MMP2MMP8MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | MMP13 2049/4885MMP2 446/4885MMP8 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.