Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13969934 | 0.91 | GAA (0.61) | CACNA1BAPBA1KLF5GAAMAPT | |
| SCHEMBL13970014 | 0.84 | GAA (0.51) | CACNA1BAPBA1KLF5GAAMAPT | |
| SCHEMBL3675364 | 0.83 | MAPT (0.65) | CACNA1BAPBA1KLF5GAAMAPT | |
| SCHEMBL13970135 | 0.78 | PKM (0.59) | GAAMAPTNPSR1PKMMEN1 | |
| SCHEMBL12847465 | 0.78 | HDAC1 (0.45) | CACNA1BAPBA1KLF5GAAMAPT | |
| SCHEMBL12847464 | 0.77 | HDAC1 (0.51) | CACNA1BAPBA1KLF5GAAMAPT | |
| SCHEMBL12790208 | 0.76 | MAPT (0.54) | CACNA1BAPBA1KLF5GAAMAPT | |
| SCHEMBL252991 | 0.75 | ALDH1A1 (0.66) | CACNA1BAPBA1KLF5GAAMAPT | |
| SCHEMBL3644534 | 0.75 | MAPT (0.74) | CACNA1BAPBA1KLF5GAAMAPT | |
| SCHEMBL12790419 | 0.75 | CSNK2A1 (0.51) | CACNA1BAPBA1KLF5GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009002534-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | GILEAD COLORADO, INC. (US) | 2008-12-31 | — | — | WO | disclosed |