Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313288 | 0.96 | ACHE (0.79) | ACHE | |
| SCHEMBL8541296 | 0.89 | ACHE (0.88) | ACHE | |
| SCHEMBL13784473 | 0.82 | ACHE (0.71) | ACHE | |
| SCHEMBL9218494 | 0.82 | ACHE (0.66) | ACHE | |
| SCHEMBL25341924 | 0.82 | ACHE (1.00) | ACHE | |
| SCHEMBL31053950 | 0.82 | ACHE (1.00) | ACHE | |
| SCHEMBL9827604 | 0.81 | ACHE (0.69) | ACHE | |
| SCHEMBL28441280 | 0.80 | ACHE (0.77) | ACHE | |
| SCHEMBL21309370 | 0.80 | ACHE (0.59) | ACHE | |
| SCHEMBL7476248 | 0.79 | SIRT1 (0.66) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173724-B1 | QUINAZOLINONE COMPOUNDS AND METHODS OF USE THEREOF | ARQULE INC (US) | 2012-12-05 | — | — | EP | disclosed |
| WO-2009002808-A2 | QUINAZOLINONE COMPOUNDS AND METHODS OF USE THEREOF | ARQULE, INC. (US) | 2008-12-31 | — | — | WO | disclosed |