Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | DRD5 | P21918 | 2/20 | 0.35 |
| ▸ | AOC2 | O75106 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4755710 | 0.99 | AVPR1A (0.38) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| Hydrochloric Acid SCHEMBL4755711 | 0.99 | AVPR1A (0.38) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| SCHEMBL4755169 | 0.86 | AVPR1A (0.39) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| SCHEMBL4789685 | 0.86 | AVPR1A (0.39) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| SCHEMBL4755166 | 0.86 | AVPR1A (0.39) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| SCHEMBL4755627 | 0.85 | AVPR1A (0.37) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| SCHEMBL4755622 | 0.85 | AVPR1A (0.37) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| SCHEMBL4789614 | 0.84 | AVPR1A (0.38) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| SCHEMBL4755635 | 0.84 | AVPR1A (0.38) | AVPR1ADRD1DRD5AOC2KCNH2 | |
| SCHEMBL4755639 | 0.84 | AVPR1A (0.38) | AVPR1ADRD1DRD5AOC2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |