Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | AOC2 | O75106 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755627 | 1.00 | AVPR1A (0.37) | AVPR1AMCHR1DRD1DRD5LOXL2 | |
| SCHEMBL4755635 | 0.90 | AVPR1A (0.38) | AVPR1AMCHR1DRD1DRD5AOC2 | |
| SCHEMBL4755639 | 0.90 | AVPR1A (0.38) | AVPR1AMCHR1DRD1DRD5AOC2 | |
| SCHEMBL13985415 | 0.87 | AVPR1A (0.36) | AVPR1AMCHR1DRD1DRD5AOC2 | |
| SCHEMBL13985528 | 0.86 | MCHR1 (0.38) | AVPR1AMCHR1DRD1DRD5KCNH2 | |
| SCHEMBL13985222 | 0.85 | AVPR1A (0.39) | AVPR1AMCHR1DRD1DRD5AOC2 | |
| SCHEMBL4753777 | 0.85 | MCHR1 (0.35) | AVPR1AMCHR1DRD1DRD5AOC2 | |
| SCHEMBL4753779 | 0.85 | MCHR1 (0.35) | AVPR1AMCHR1DRD1DRD5AOC2 | |
| Hydrochloric Acid SCHEMBL4755711 | 0.84 | AVPR1A (0.38) | AVPR1AMCHR1DRD1DRD5AOC2 | |
| Hydrochloric Acid SCHEMBL4755710 | 0.84 | AVPR1A (0.38) | AVPR1AMCHR1DRD1DRD5AOC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |