Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13941363 | 0.90 | TP53 (0.48) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13966280 | 0.90 | TP53 (0.48) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13985157 | 0.90 | TP53 (0.48) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13941574 | 0.84 | TP53 (0.43) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13941359 | 0.84 | PLK4 (0.49) | MEN1KMT2ANPC1RAB9AMGLL | |
| SCHEMBL13985291 | 0.84 | TP53 (0.45) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL889783 | 0.83 | PLK4 (0.47) | MGLLESRRGFAAH | |
| SCHEMBL13941566 | 0.82 | PLK4 (0.47) | MEN1KMT2ANPC1RAB9AMGLL | |
| SCHEMBL13985372 | 0.82 | RAB9A (0.52) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13985375 | 0.80 | RAB9A (0.62) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156573-A1 | KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH | PROVID PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |