Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 5/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985375 | 0.94 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL13985370 | 0.93 | NPC1 (0.64) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL13985289 | 0.91 | MGLL (0.49) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL13985373 | 0.89 | FAAH (0.63) | RAB9ANPC1SMN1; SMN2CYP1A2NPSR1 | |
| SCHEMBL2949066 | 0.88 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL889783 | 0.87 | PLK4 (0.47) | MGLLFAAHESRRG | |
| Hydrochloric Acid SCHEMBL9577859 | 0.86 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13985368 | 0.86 | KMT2A (0.50) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL13985381 | 0.85 | KMT2A (0.48) | RAB9ANPC1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL10054978 | 0.84 | KDM4E (0.63) | RAB9ASMN1; SMN2CYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765802-B2 | Kinase inhibitors, compositions thereof, and methods of use therewith | PROVID PHARMACEUTICALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| WO-2008156573-A1 | KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH | PROVID PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |