Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17961055 | 0.82 | TSHR (0.51) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL3409345 | 0.82 | TDP1 (0.44) | CYP3A4ALDH1A1LMNAKDM4EGAA | |
| Ammonia Solution, Strong SCHEMBL15940166 | 0.81 | TSHR (0.59) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL8598930 | 0.81 | ALDH1A1 (0.47) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL8596810 | 0.81 | ALDH1A1 (0.47) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL9424810 | 0.80 | MEN1 (0.45) | ALDH1A1LMNAKDM4EMAPTGLA | |
| SCHEMBL14990402 | 0.80 | ALDH1A1 (0.61) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL31310821 | 0.80 | ALDH1A1 (0.61) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL10387044 | 0.79 | TSHR (0.57) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL434453 | 0.79 | TSHR (0.51) | TSHRCYP3A4MAPK1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10641768-B2 | Methods and kits for decreasing interferences from leukocytes in specific binding assays | ABBOTT JAPAN CO. LTD. (JP) | 2020-05-05 | — | — | US | claimed |
| US-20140072996-A1 | METHODS AND KITS FOR DETECTING HEMOGLOBIN IN TEST SAMPLES | ABBOTT LABORATORIES (US) | 2014-03-13 | — | — | US | claimed |
| US-8574858-B2 | Autoantibody enhanced immunoassays and kits | ABBOTT LABORATORIES (US) | 2013-11-05 | — | — | US | claimed |
| EP-2598534-A1 | ANTIBODIES RELATING TO PIVKA-II AND USES THEREOF | Abbott Laboratories (US) | 2013-06-05 | — | — | EP | claimed |
| US-20130029353-A1 | AUTOANTIBODY ENHANCED IMMUNOASSAYS AND KITS | ABBOTT LABORATORIES (US) | 2013-01-31 | — | — | US | claimed |
| WO-2013008900-A1 | METHODS AND KITS FOR DECREASING INTERFERENCES FROM LEUKOCYTES IN SPECIFIC BINDING ASSAYS | ABBOTT JAPAN CO. LTD. (JP) | 2013-01-17 | — | — | WO | claimed |
| US-20130011826-A1 | METHODS AND KITS FOR DECREASING INTERFERENCES FROM LEUKOCYTES IN SPECIFIC BINDING ASSAYS | ABBOTT LABORATORIES (US) | 2013-01-10 | — | — | US | claimed |
| US-8304201-B2 | Autoantibody enhanced immunoassays and kits | ABBOTT LABORATORIES (US) | 2012-11-06 | — | — | US | claimed |
| US-20120270258-A1 | METHODS AND KITS FOR DETECTING HEMOGLOBIN IN TEST SAMPLES | ABBOTT LABORATORIES (US) | 2012-10-25 | — | — | US | claimed |
| EP-2507626-A1 | PEPTIDE REAGENTS AND METHOD FOR INHIBITING AUTOANTIBODY ANTIGEN BINDING | Abbott Laboratories (US) | 2012-10-10 | — | — | EP | claimed |
| US-20090286256-A1 | ISOLATED HUMAN AUTOANTIBODIES TO NATRIURETIC PEPTIDES AND METHODS AND KITS FOR DETECTING HUMAN AUTOANTIBODIES TO NATRIURETIC PEPTIDES | ABBOTT LABORATORIES (US) | 2009-11-19 | — | — | US | claimed |
| US-20090286329-A1 | ISOLATED HUMAN AUTOANTIBODIES TO NATRIURETIC PEPTIDES AND METHODS AND KITS FOR DETECTING HUMAN AUTOANTIBODIES TO NATRIURETIC PEPTIDES | ABBOTT LABORATOIRES (US) | 2009-11-19 | — | — | US | claimed |
| WO-2009131963-A2 | METHOD AND KIT FOR ASSESSING THE SUITABILITY OF ERYTHROCYTES FOR TRANSFUSION | ABBOTT LABORATORIES (US) | 2009-10-29 | — | — | WO | claimed |
| US-20090263845-A1 | METHOD AND KIT FOR ASSESSING THE SUITABILITY OF ERYTHROCYTES FOR TRANSFUSION | ABBOTT LABORATORIES (US) | 2009-10-22 | — | — | US | claimed |
| WO-2009085883-A1 | THE ACCURACY OF MYELOPEROXIDASE ASSAYS AND THE DETECTION OF MYELOPEROXIDASE AUTOANTIBODIES | ABBOTT LABORATORIES (US) | 2009-07-09 | — | — | WO | claimed |
| US-20090162876-A1 | MYELOPEROXIDASE ASSAYS | ABBOTT LABORATORIES (US) | 2009-06-25 | — | — | US | claimed |
| WO-2009076330-A1 | STABILIZING COMPOSITIONS, METHODS AND KITS FOR CHEMILUMINESCENT ASSAYS | ABBOTT LABORATORIES (US) | 2009-06-18 | — | — | WO | claimed |
| US-20090148879-A1 | Stabilizing Compositions, Methods and Kits for Chemiluminescent Assays | ABBOTT LABORATORIES | 2009-06-11 | — | — | US | claimed |
| WO-2008124749-A1 | ACRIDINIUM PHENYL ESTERS USEFUL IN THE ANALYSIS OF BIOLOGICAL SAMPLES | ABBOTT LABORATORIES (US) | 2008-10-16 | — | — | WO | claimed |
| US-20080248493-A1 | ACRIDINIUM PHENYL ESTERS USEFUL IN THE ANALYSIS OF BIOLOGICAL SAMPLES | ABBOTT LABORATORIES | 2008-10-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286329-A1 | ISOLATED HUMAN AUTOANTIBODIES TO NATRIURETIC PEPTIDES AND METHODS AND KITS FOR DETECTING HUMAN AUTOANTIBODIES TO NATRIURETIC PEPTIDES | NPPA, NPR1, NPR3 | TSHR 180/4885CYP3A4 4880/4885MAPK1 3772/4885 |
| US-20090286256-A1 | ISOLATED HUMAN AUTOANTIBODIES TO NATRIURETIC PEPTIDES AND METHODS AND KITS FOR DETECTING HUMAN AUTOANTIBODIES TO NATRIURETIC PEPTIDES | NPPA, NPR1, NPR3 | TSHR 180/4885CYP3A4 4880/4885MAPK1 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.