Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | BACE1 | P56817 | 7/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456810 | 0.88 | ACHE (0.57) | CARM1PRMT6MEN1KMT2AHRH3 | |
| SCHEMBL3456633 | 0.87 | ACHE (0.59) | CARM1PRMT6MEN1KMT2AHRH3 | |
| SCHEMBL27962597 | 0.82 | BCHE (0.62) | CARM1PRMT6MEN1KMT2AACHE | |
| SCHEMBL12672171 | 0.77 | HRH3 (0.55) | CARM1PRMT6MEN1KMT2AHRH3 | |
| SCHEMBL17102128 | 0.75 | CARM1 (0.65) | CARM1PRMT6MEN1KMT2AHRH3 | |
| SCHEMBL3456800 | 0.72 | HRH3 (0.54) | CARM1PRMT6MEN1KMT2AHRH3 | |
| SCHEMBL18873644 | 0.70 | KDM1A (0.47) | CARM1PRMT6KDM1A | |
| SCHEMBL3457686 | 0.69 | ACHE (0.64) | CARM1PRMT6MEN1KMT2AHRH3 | |
| SCHEMBL3456705 | 0.69 | ACHE (0.65) | CARM1PRMT6MEN1KMT2AHRH3 | |
| SCHEMBL25570453 | 0.69 | ACHE (0.52) | CARM1PRMT6MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462620-B2 | Pyrimidinone derivatives and their use in the treatment of atherosclerosis | SMITHKLINE BEECHAM, PLC (GB) | 2008-12-09 | — | — | US | disclosed |