Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990211 | 0.79 | NQO2 (0.35) | NQO2TSHR | |
| SCHEMBL13990198 | 0.74 | GAA (0.48) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL524175 | 0.71 | GAA (0.49) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL11253706 | 0.70 | GAA (0.51) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL2811429 | 0.69 | GAA (0.53) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL1361427 | 0.68 | KDM4E (0.51) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL22081931 | 0.68 | ABL1 (0.49) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL29608598 | 0.68 | GAA (0.46) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL2525608 | 0.68 | GAA (0.46) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL8178854 | 0.68 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522967-B2 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY INTERNATIONAL INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20080306179-A1 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY SIRONA INC. | 2008-12-11 | — | — | US | disclosed |