Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705197 | 0.83 | GAA (0.65) | GAAKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13990199 | 0.78 | GABRG2 (0.37) | GAAKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL13990213 | 0.74 | KDM4E (0.37) | GAAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL2726928 | 0.72 | GAA (0.54) | GAAKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5099640 | 0.71 | GAA (0.50) | GAAKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29706660 | 0.71 | GAA (0.50) | GAAKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1403643 | 0.71 | GAA (0.72) | GAAKDM4ECYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL18000077 | 0.71 | GAA (0.47) | GAAKDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1165503 | 0.71 | GAA (0.62) | GAAKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL15832745 | 0.70 | KDM4E (0.56) | GAAKDM4ECYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522967-B2 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY INTERNATIONAL INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20080306179-A1 | Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby | DENTSPLY SIRONA INC. | 2008-12-11 | — | — | US | disclosed |