Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16501713 | 0.90 | NPSR1 (0.49) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13992478 | 0.89 | NPSR1 (0.44) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10046768 | 0.86 | NPSR1 (0.49) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL15698374 | 0.85 | BCHE (0.43) | NPSR1ALDH1A1TSHRGAAHTT | |
| SCHEMBL13992481 | 0.82 | NPSR1 (0.52) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14213209 | 0.82 | CYP1A2 (0.57) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16501714 | 0.81 | NPSR1 (0.50) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10046737 | 0.78 | THRA (0.42) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13992476 | 0.78 | LGALS1 (0.63) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13992477 | 0.77 | NPSR1 (0.40) | NPSR1ALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300164-A1 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300164-A1 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making | CLSPN, BID, CALU | NPSR1 1564/4885ALDH1A1 4794/4885CYP1A2 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.