Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS1 | P09382 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13992489 | 0.90 | LGALS1 (0.55) | LGALS1ALDH1A1NPSR1KMT2ACYP1A2 | |
| SCHEMBL10046739 | 0.87 | LGALS1 (0.55) | LGALS1ALDH1A1NPSR1KMT2ACYP1A2 | |
| SCHEMBL14213241 | 0.86 | LGALS1 (0.54) | LGALS1ALDH1A1NPSR1KMT2ACYP1A2 | |
| SCHEMBL14213201 | 0.82 | LGALS1 (0.57) | LGALS1ALDH1A1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL10046775 | 0.82 | KMT2A (0.51) | LGALS1ALDH1A1KMT2ATHRBPOLB | |
| SCHEMBL13992481 | 0.79 | NPSR1 (0.52) | LGALS1ALDH1A1NPSR1CYP1A2CYP2D6 | |
| SCHEMBL13992479 | 0.78 | NPSR1 (0.54) | LGALS1ALDH1A1NPSR1CYP1A2CYP2D6 | |
| Otx-008 SCHEMBL29423596 | 0.77 | LGALS1 (1.00) | LGALS1ALDH1A1NPSR1KMT2ACYP1A2 | |
| Otx-008 SCHEMBL28666062 | 0.77 | LGALS1 (1.00) | LGALS1ALDH1A1NPSR1KMT2ACYP1A2 | |
| SCHEMBL10046768 | 0.76 | NPSR1 (0.49) | LGALS1ALDH1A1NPSR1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243415-A1 | COMPOUNDS INHIBITING GALECTIN-1 EXPRESSION, CANCER CELL PROLIFERATION, INVASION, AND TUMORIGENESIS | ONCOETHIX SA (CH) | 2014-08-28 | — | — | US | disclosed |
| US-20080300164-A1 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300164-A1 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making | CLSPN, BID, CALU | LGALS1 429/4885ALDH1A1 4794/4885NPSR1 1564/4885 |
| US-20140243415-A1 | COMPOUNDS INHIBITING GALECTIN-1 EXPRESSION, CANCER CELL PROLIFERATION, INVASION, AND TUMORIGENESIS | LGALS1, LGALS2, LGALS3 | LGALS1 1/4885ALDH1A1 958/4885NPSR1 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.