Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TXN | P10599 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | C1R | P00736 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30014038 | 0.81 | ACHE (0.42) | ACHEMPOKDM4EKMT2ABCHE | |
| SCHEMBL1994310 | 0.81 | ACHE (0.42) | ACHEMPOKDM4EKMT2ABCHE | |
| SCHEMBL14843701 | 0.78 | MPO (0.54) | ACHEMPOKDM4EKMT2ABCHE | |
| SCHEMBL29224064 | 0.78 | HTT (0.50) | ACHEMPOKDM4EKMT2ABCHE | |
| SCHEMBL26684310 | 0.73 | BCKDK (0.42) | ACHEKMT2A | |
| SCHEMBL5785876 | 0.73 | MAPK14 (0.44) | ACHEMPOKDM4E | |
| SCHEMBL26684627 | 0.71 | GRM2 (0.42) | ACHEMPO | |
| SCHEMBL12481107 | 0.70 | ACHE (0.42) | ACHEMPOKDM4EKMT2AHTT | |
| SCHEMBL23202854 | 0.69 | ACHE (0.42) | ACHEMPOKDM4EKMT2ABCHE | |
| SCHEMBL1991118 | 0.69 | BCHE (0.42) | ACHEMPOKDM4EKMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003131-A1 | AMINOPYRROLIDINE COMPOUND | Taisho Pharmaceutical Co. Ltd. (JP) | 2008-12-17 | — | — | EP | disclosed |