Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3104892 | 0.86 | MEN1 (0.45) | MEN1KMT2APTGS2PTGS1TGFBR1 | |
| SCHEMBL3100346 | 0.85 | MEN1 (0.52) | MEN1KMT2APTGS2PTGS1PLAT | |
| SCHEMBL3096791 | 0.81 | MEN1 (0.48) | MEN1KMT2APTGS2PTGS1CYP1A2 | |
| SCHEMBL3093919 | 0.80 | KCNJ6 (0.50) | MEN1KMT2APTGS2PTGS1CYP1A2 | |
| SCHEMBL3093801 | 0.79 | MEN1 (0.46) | MEN1KMT2APTGS2PTGS1PLAT | |
| SCHEMBL3105412 | 0.78 | PTGS2 (0.46) | MEN1KMT2APTGS2PTGS1PLAT | |
| SCHEMBL3100756 | 0.75 | CARM1 (0.44) | MEN1KMT2APLATKCNJ6KCNJ3 | |
| SCHEMBL3097657 | 0.74 | MAPT (0.42) | MEN1KMT2APLATCYP1A2CYP3A4 | |
| SCHEMBL14504449 | 0.72 | MGLL (0.52) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3093815 | 0.72 | MAPT (0.47) | MEN1KMT2ATGFBR1PLATKCNJ6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009006-A1 | UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2008-12-31 | — | — | EP | disclosed |