Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 2/20 | 0.50 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.48 |
| ▸ | RPA1 | P27694 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | KHK | P50053 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100346 | 0.94 | MEN1 (0.52) | KCNJ6KCNJ3MEN1KMT2ARPA1 | |
| SCHEMBL3096791 | 0.90 | MEN1 (0.48) | MEN1KMT2APTGS2PTGS1CYP1A2 | |
| SCHEMBL3093801 | 0.84 | MEN1 (0.46) | KCNJ6KCNJ3MEN1KMT2ARPA1 | |
| SCHEMBL2598511 | 0.84 | L3MBTL1 (0.51) | KCNJ6KCNJ3MEN1KMT2AKCNJ5 | |
| SCHEMBL3104892 | 0.84 | MEN1 (0.45) | KCNJ6KCNJ3MEN1KMT2APTGS2 | |
| SCHEMBL3105412 | 0.84 | PTGS2 (0.46) | MEN1KMT2APTGS2PTGS1CACNA1B | |
| SCHEMBL13993244 | 0.80 | MEN1 (0.42) | KCNJ6KCNJ3MEN1KMT2ARPA1 | |
| SCHEMBL14504449 | 0.80 | MGLL (0.52) | KCNJ6KCNJ3KCNJ5RPA1PTGS2 | |
| SCHEMBL3097657 | 0.80 | MAPT (0.42) | KCNJ6KCNJ3MEN1KMT2AKCNJ5 | |
| SCHEMBL3098701 | 0.79 | KCNJ6 (0.51) | KCNJ6KCNJ3KCNJ5RPA1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2009006-A1 | UREIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | TORAY INDUSTRIES, INC. (JP) | 2008-12-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234395-A1 | UREIDE DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | UROD, UTS2R, SLC14A1 | KCNJ6 2225/4885KCNJ3 2066/4885MEN1 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.