Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25754057 | 0.92 | ESR1 (0.50) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL8206761 | 0.90 | ESR1 (0.70) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL14308417 | 0.88 | CNR2 (0.49) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL9148067 | 0.87 | ESR1 (0.50) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL14163852 | 0.86 | L3MBTL1 (0.50) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL6935203 | 0.86 | L3MBTL1 (0.50) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL13720599 | 0.86 | L3MBTL1 (0.50) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL13049481 | 0.86 | ALDH1A1 (0.52) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL13720556 | 0.86 | L3MBTL1 (0.50) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL14069614 | 0.86 | L3MBTL1 (0.50) | ESR1ESR2ALDH1A1CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080303422-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |