Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.46 |
| ▸ | CDK9 | P50750 | 19/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005617 | 0.90 | TBK1 (0.48) | CCNT1CDK9TBK1 | |
| SCHEMBL14500613 | 0.89 | CCNT1 (0.39) | CCNT1CDK9 | |
| SCHEMBL5661845 | 0.84 | CCNT1 (0.45) | CCNT1CDK9 | |
| SCHEMBL5008119 | 0.84 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL13994257 | 0.84 | CCNT1 (0.47) | CCNT1CDK9TBK1 | |
| SCHEMBL14530348 | 0.79 | CCNT1 (0.39) | CCNT1CDK9 | |
| SCHEMBL5005791 | 0.79 | CDK9 (0.47) | CCNT1CDK9TBK1 | |
| SCHEMBL13994533 | 0.78 | RIPK2 (0.42) | CCNT1CDK9 | |
| SCHEMBL14500615 | 0.77 | CCNT1 (0.46) | CCNT1CDK9 | |
| SCHEMBL14500327 | 0.76 | CCNT1 (0.46) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |