Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.58 |
| ▸ | MPO | P05164 | 9/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399411 | 0.91 | MPO (0.65) | HTR2ATRPM8MPOHTR1AKMT2A | |
| SCHEMBL4633110 | 0.91 | HTR2A (0.54) | HTR2ATRPM8MPOHTR1AKMT2A | |
| SCHEMBL1399398 | 0.86 | HTR2A (0.58) | HTR2ATRPM8MPOHTR1AKMT2A | |
| SCHEMBL1399440 | 0.86 | HTR2A (0.58) | HTR2ATRPM8MPOHTR1AKMT2A | |
| SCHEMBL1399318 | 0.84 | HTR2A (0.62) | HTR2ATRPM8MPOHTR1AIDO1 | |
| SCHEMBL4632232 | 0.84 | HTR2A (0.65) | HTR2ATRPM8MPOHTR1AKMT2A | |
| SCHEMBL1399286 | 0.83 | MPO (0.58) | HTR2ATRPM8MPOHTR1AKMT2A | |
| SCHEMBL1399265 | 0.83 | HTR2A (0.60) | HTR2ATRPM8MPOHTR1AKMT2A | |
| SCHEMBL1399204 | 0.82 | IDO1 (0.54) | HTR2ATRPM8MPOHTR1AIDO1 | |
| SCHEMBL1399332 | 0.81 | MPO (0.62) | HTR2ATRPM8MPOHTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860100-B1 | 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI | LUNDBECK & CO AS H (DK) | 2011-03-02 | — | — | EP | claimed |