SCHEMBL1399489

SCHEMBL1399489

C=CCc1ccccc1OC(C)=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.55
LMNA P02545 2/20 0.53
MAPT P10636 1/20 0.53
ALOX12 P18054 1/20 0.53
NCOA1 Q15788 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
NCOA3 Q9Y6Q9 1/20 0.53
PTGS1 P23219 2/20 0.51
ELANE P08246 1/20 0.49
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 2/20 0.48
PTGS2 P35354 3/20 0.47
TSHR P16473 2/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
HPGD P15428 1/20 0.47
GGT1 P19440 1/20 0.47
BLM P54132 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31112657 1.00 ALOX5 (0.55) ALOX5LMNAMAPTALOX12NCOA1
Bromide SCHEMBL7277996 0.98 ALOX5 (0.53) ALOX5LMNAMAPTALOX12NCOA1
SCHEMBL3398506 0.87 KDM4E (0.46) ALOX5LMNAMAPTALOX12NCOA1
SCHEMBL278521 0.86 KDM4E (0.49) LMNAELANEKDM4EALDH1A1TSHR
SCHEMBL16050965 0.86 PTGS2 (0.50) LMNAPTGS1ELANEKDM4EALDH1A1
SCHEMBL16163500 0.86 PTGS2 (0.50) LMNAPTGS1ELANEKDM4EALDH1A1
SCHEMBL7157956 0.86 KDM4E (0.49) LMNAELANEKDM4EALDH1A1TSHR
SCHEMBL7856423 0.85 GABRA1 (0.53) ALOX5LMNAMAPTALOX12NCOA1
SCHEMBL7857061 0.85 MAPK1 (0.51) ALOX5LMNAMAPTALOX12NCOA1
SCHEMBL5448543 0.84 KDM4E (0.48) LMNAELANEKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143059-A Synthesis method of benzofuranone 常州大学 2023-12-01 CN claimed
CN-116715572-A Synthesis method of o-hydroxyphenylacetic acid 常州大学 2023-09-08 CN claimed
US-5354264-A Gas pressure driven infusion system by hydrogel electrolysis INSUTECH, INC. (US) 1994-10-11 US claimed
US-20250208467-A1 WAVELENGTH CONVERSION MEMBER AND MANUFACTURING METHOD THEREFOR NICHIA CORPORATION (JP) 2025-06-26 US disclosed
CN-117164499-A Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors 拜奥克里斯特制药公司 2023-12-05 CN disclosed
CN-117143059-A Synthesis method of benzofuranone 常州大学 2023-12-01 CN disclosed
CN-117143059-A Synthesis method of benzofuranone 常州大学 2023-12-01 CN disclosed
WO-2023176509-A1 WAVELENGTH CONVERSION MEMBER AND MANUFACTURING METHOD THEREFOR 日亜化学工業株式会社 2023-09-21 WO disclosed
CN-116715572-A Synthesis method of o-hydroxyphenylacetic acid 常州大学 2023-09-08 CN disclosed
CN-116715572-A Synthesis method of o-hydroxyphenylacetic acid 常州大学 2023-09-08 CN disclosed
WO-2023048229-A1 POLYMERIZABLE COMPOSITION, CURED PRODUCT, WAVELENGTH CONVERSION MEMBER, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE 富士フイルム株式会社 2023-03-30 WO disclosed
EP-0060668-A1 N-carboxyalkyl dipeptide derivatives and pharmaceutical compositions thereof BEECHAM GROUP PLC (GB) 1982-09-22 EP disclosed
US-4308180-A TIRE TREADS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-29 US disclosed
US-4240974-A 1,2,3,4,9,9-HEXAHALO-1,4-DIHYDRO-1,4-METHANO-NAPHTHALENE-5,8 -DISULFONATE LITTLE JULIAN R (US) 1980-12-23 US disclosed
US-4174457-A Carbamate UNIROYAL, INC. (US) 1979-11-13 US disclosed
US-4080408-A FIRE RETARDANTS UNIROYAL, INC. (US) 1978-03-21 US disclosed
US-4058568-A FIRE RETARDANT UNIROYAL, INC. (US) 1977-11-15 US disclosed
US-4009200-A FIREPROOFING POLYMERS UNIROYAL, INC. (US) 1977-02-22 US disclosed
US-3979463-A CONDENSED WITH ALDEHYDES, WATER REPELLANT, OIL REPELLANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-09-07 US disclosed
US-3931329-A OIL AND WATER REPELLENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-01-06 US disclosed