Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL20917641 | 1.00 | TDP1 (0.47) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL9300252 | 1.00 | TDP1 (0.47) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL8678385 | 0.97 | TDP1 (0.45) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL3284766 | 0.88 | TDP1 (0.43) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL3117725 | 0.88 | ALDH1A1 (0.44) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL1399502 | 0.88 | PAOX (0.44) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL28271532 | 0.88 | TDP1 (0.43) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL18222437 | 0.88 | — | — | |
| Methacrylic Acid SCHEMBL4931388 | 0.88 | — | — | |
| Methacrylic Acid SCHEMBL30238728 | 0.86 | PAOX (0.54) | TDP1GABRR1PAOXTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117487080-A | Super-absorbent resin and application thereof in chlorine dioxide slow-release air disinfection powder | 辽宁大学 | 2024-02-02 | — | — | CN | claimed |
| EP-3172299-B1 | FABRIC AND HOME CARE TREATMENT COMPOSITIONS | PROCTER & GAMBLE (US) | 2019-09-25 | — | — | EP | claimed |
| US-10407646-B2 | Treatment compositions | THE PROCTER & GAMBLE COMPANY (US) | 2019-09-10 | — | — | US | claimed |
| US-20190225916-A1 | TREATMENT COMPOSITIONS | PROCTER & GAMBLE (US) | 2019-07-25 | — | — | US | claimed |
| US-10266792-B2 | Treatment compositions | THE PROCTER & GAMBLE COMPANY (US) | 2019-04-23 | — | — | US | claimed |
| EP-3172299-A1 | FABRIC AND HOME CARE TREATMENT COMPOSITIONS | The Procter and Gamble Company (US) | 2017-05-31 | — | — | EP | claimed |
| US-20160032220-A1 | TREATMENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY | 2016-02-04 | — | — | US | claimed |
| WO-2016014733-A1 | FABRIC AND HOME CARE TREATMENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2016-01-28 | — | — | WO | claimed |
| CN-113969157-B | Compact reservoir CO2Flooding multi-scale channeling control system and preparation method thereof | 西南石油大学 | 2022-05-24 | — | — | CN | disclosed |
| EP-3172299-B1 | FABRIC AND HOME CARE TREATMENT COMPOSITIONS | PROCTER & GAMBLE (US) | 2019-09-25 | — | — | EP | disclosed |
| US-10407646-B2 | Treatment compositions | THE PROCTER & GAMBLE COMPANY (US) | 2019-09-10 | — | — | US | disclosed |
| US-20190225916-A1 | TREATMENT COMPOSITIONS | PROCTER & GAMBLE (US) | 2019-07-25 | — | — | US | disclosed |
| US-10266792-B2 | Treatment compositions | THE PROCTER & GAMBLE COMPANY (US) | 2019-04-23 | — | — | US | disclosed |
| CN-105008421-B | Arylate styrene acrylonitrile polymer and thermoplastic resin composition | LG化学株式会社 | 2018-02-27 | — | — | CN | disclosed |
| US-7030174-B2 | Provides high weather resistance, images having a high printed density by using pigment inks, and have a wide color reproducing range; capable of performing text printing at a high printing density and with excellent abrasion resistance | SEIKO EPSON CORPORATION (JP) | 2006-04-18 | — | — | US | disclosed |
| US-6767090-B2 | Ink set for ink-jet recording | SEIKO EPSON CORPORATION (JP) | 2004-07-27 | — | — | US | disclosed |
| EP-1321495-A1 | INK SET FOR INK JET-JET RECORDING, METHOD FOR INK-JET RECORDING AND RECORDED MATTER | SEIKO EPSON CORPORATION (JP) | 2003-06-25 | — | — | EP | disclosed |
| US-20030097961-A1 | Ink set for ink-jet recording | SEIKO EPSON CORPORATION (JP) | 2003-05-29 | — | — | US | disclosed |
| US-20030078320-A1 | Ink set for ink jet-jet recording , method for ink-jet recording and recorded matter | SEIKO EPSON CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1291397-A1 | INK SET FOR INK-JET RECORDING | SEIKO EPSON CORPORATION (JP) | 2003-03-12 | — | — | EP | disclosed |