Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL1399516 | 1.00 | TDP1 (0.47) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL9300252 | 1.00 | TDP1 (0.47) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL8678385 | 0.97 | TDP1 (0.45) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL3284766 | 0.88 | TDP1 (0.43) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL3117725 | 0.88 | ALDH1A1 (0.44) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL1399502 | 0.88 | PAOX (0.44) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL28271532 | 0.88 | TDP1 (0.43) | TDP1GLRA1SLC6A9OR51E2GABRR1 | |
| Methacrylic Acid SCHEMBL18222437 | 0.88 | — | — | |
| Methacrylic Acid SCHEMBL4931388 | 0.88 | — | — | |
| Methacrylic Acid SCHEMBL30238728 | 0.86 | PAOX (0.54) | TDP1GABRR1PAOXTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092166-A1 | A PLURALITY OF MICROCAPSULES AND USE THEREOF IN POLYMERS | CALYXIA SAS (FR) | 2026-04-02 | — | — | US | disclosed |
| EP-4658072-A1 | MICROCAPSULES CONTAINING AGROCHEMICAL INGREDIENTS | Calyxia (FR) | 2025-12-10 | — | — | EP | disclosed |
| EP-4658075-A1 | CLOMAZONE MICROCAPSULES | Calyxia (FR) | 2025-12-10 | — | — | EP | disclosed |
| US-20250360478-A1 | PROCESS FOR THE MANUFACTURE OF MICROCAPSULES AND MICROCAPSULES | CALYXIA SAS (FR) | 2025-11-27 | — | — | US | disclosed |
| EP-4637986-A1 | A PLURALITY OF MICROCAPSULES AND USE THEREOF IN POLYMERS | Calyxia SAS (FR) | 2025-10-29 | — | — | EP | disclosed |
| US-20250325947-A1 | DOUBLE EMULSION AND CAPSULES | CALYXIA (FR) | 2025-10-23 | — | — | US | disclosed |
| EP-4608548-A1 | PROCESS FOR THE MANUFACTURE OF MICROCAPSULES AND MICROCAPSULES | Calyxia SAS (FR) | 2025-09-03 | — | — | EP | disclosed |
| US-20250257293-A1 | CARE PRODUCT COMPOSITIONS HAVING IMPROVED OLFACTORY PROPERTIES | CALYXIA (FR) | 2025-08-14 | — | — | US | disclosed |
| US-20250250516-A1 | DETERGENT COMPOSITIONS HAVING IMPROVED OLFACTORY PROPERTIES | CALYXIA (FR) | 2025-08-07 | — | — | US | disclosed |
| WO-2025132932-A1 | A PLURALITY OF MICROCAPSULES AND USE THEREOF IN POLYMERS | CALYXIA SAS (FR) | 2025-06-26 | — | — | WO | disclosed |
| EP-3624932-A1 | METHOD FOR PREPARING BIODEGRADABLE CAPSULES AND CAPSULES OBTAINED | Calyxia (FR) | 2020-03-25 | — | — | EP | disclosed |
| US-20200047144-A1 | METHOD FOR PREPARNG CAPSULES COMPRISING AT LEAST ONE WATER-SOLUBLE OR HYDROPHILIC SUBSTANCE AND CAPSULES OBTAINED THEREFROM | CALYXIA (FR) | 2020-02-13 | — | — | US | disclosed |
| US-20200038297-A1 | METHOD FOR PRODUCING CAPSULES COMPRISING AT LEAST ONE VOLATILE COMPOUND, AND RESULTING CAPSULES | CAPSUM (FR) | 2020-02-06 | — | — | US | disclosed |
| EP-3600641-A1 | METHOD FOR PREPARING CAPSULES COMPRISING AT LEAST ONE WATER-SOLUBLE OR HYDROPHILIC SUBSTANCE AND CAPSULES OBTAINED THEREFROM | Calyxia (FR) | 2020-02-05 | — | — | EP | disclosed |
| EP-3600643-A1 | METHOD FOR PREPARING CAPSULES COMPRISING AT LEAST ONE VOLATILE COMPOUND AND CAPSULES OBTAINED THEREFROM | Calyxia (FR) | 2020-02-05 | — | — | EP | disclosed |
| EP-3600642-A1 | METHOD FOR PREPARING CAPSULES WITH IMPROVED RETENTION PROPERTIES AND CAPSULES OBTAINED THEREFROM | Calyxia (FR) | 2020-02-05 | — | — | EP | disclosed |
| EP-3548521-A1 | METHOD FOR PREPARING MICROCAPSULES AND MICROPARTICLES OF CONTROLLED SIZE | Calyxia (FR) | 2019-10-09 | — | — | EP | disclosed |
| EP-3548529-A1 | PROCESS FOR PREPARING MICROCAPSULES OF CONTROLLED SIZE COMPRISING A PHOTOPOLYMERIZATION STEP | Calyxia (FR) | 2019-10-09 | — | — | EP | disclosed |
| US-20190299185-A1 | METHOD FOR PREPARING MICROCAPSULES AND MICROPARTICLES OF CONTROLLED SIZE | CALYXIA (FR) | 2019-10-03 | — | — | US | disclosed |
| WO-2019076911-A1 | METHOD FOR PREPARING CAPSULES SENSITIVE TO PH OR UV RADIATION AND CAPSULES OBTAINED THEREFROM | CALYXIA (FR) | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092166-A1 | A PLURALITY OF MICROCAPSULES AND USE THEREOF IN POLYMERS | PHOSPHO1, DAGLA, SMCHD1 | TDP1 4040/4885GLRA1 3107/4885SLC6A9 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.