Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SCNN1A | P37088 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995431 | 0.91 | KCNH2 (0.50) | KCNH2SCNN1AMAPTKDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5015577 | 0.87 | KCNH2 (0.47) | KCNH2SCNN1AMAPTKDM4EALDH1A1 | |
| SCHEMBL5015580 | 0.83 | ALDH1A1 (0.49) | SCNN1AMAPTKDM4EALDH1A1GLA | |
| SCHEMBL13995453 | 0.81 | ALDH1A1 (0.50) | KCNH2SCNN1AMAPTKDM4EALDH1A1 | |
| SCHEMBL13995445 | 0.81 | ALDH1A1 (0.48) | SCNN1AMAPTKDM4EALDH1A1GLA | |
| SCHEMBL13995432 | 0.80 | SCNN1A (0.48) | SCNN1AMAPTKDM4EALDH1A1GLA | |
| SCHEMBL10028704 | 0.78 | SCNN1A (0.67) | KCNH2SCNN1A | |
| Trifluoroacetic Acid SCHEMBL3520459 | 0.77 | SCNN1A (0.54) | KCNH2SCNN1AMAPTKDM4EALDH1A1 | |
| SCHEMBL16383771 | 0.76 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL16383862 | 0.76 | SCNN1A (0.55) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312212-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| US-20080312212-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312212-A1 | Organic Compounds | TRPA1, TRPV1, TRPV3 | KCNH2 89/4885SCNN1A 21/4885MAPT 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.