Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.57 |
| ▸ | FAAH | O00519 | 5/20 | 0.57 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13512632 | 0.89 | MGLL (0.55) | MGLLFAAHDDAH1HSP90AA1NPSR1 | |
| SCHEMBL44044 | 0.85 | MGLL (0.54) | MGLLFAAHDDAH1HSP90AA1NPSR1 | |
| SCHEMBL17235982 | 0.85 | MGLL (0.51) | MGLLFAAHHPGDPKM | |
| Hydrochloric Acid SCHEMBL44524 | 0.84 | MGLL (0.52) | MGLLFAAHDDAH1HSP90AA1NPSR1 | |
| Hydrochloric Acid SCHEMBL443354 | 0.84 | MGLL (0.52) | MGLLFAAHDDAH1HSP90AA1NPSR1 | |
| SCHEMBL12683541 | 0.83 | MGLL (0.62) | MGLLFAAHDDAH1HSP90AA1NPSR1 | |
| SCHEMBL16508391 | 0.82 | MGLL (0.50) | MGLLFAAHALDH1A1PKM | |
| SCHEMBL514697 | 0.81 | MGLL (0.59) | MGLLFAAHDDAH1HSP90AA1NPSR1 | |
| SCHEMBL741572 | 0.81 | MGLL (0.59) | MGLLFAAHDDAH1HSP90AA1NPSR1 | |
| SCHEMBL28390770 | 0.81 | MGLL (0.56) | MGLLFAAHDDAH1HSP90AA1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080305038-A1 | Transport of Nano-and Macromolecular Structures Into Cytoplasm and Nucleus of Cells | LUDWIG-MAXIMILIANS-UNIVERSITÄT (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305038-A1 | Transport of Nano-and Macromolecular Structures Into Cytoplasm and Nucleus of Cells | NFATC1, KPNA4, KPNA1 | MGLL 4765/4885FAAH 4796/4885DDAH1 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.