Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288240 | 0.85 | DPP4 (0.55) | LMNASMN1; SMN2CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL24322759 | 0.80 | LMNA (0.62) | LMNASMN1; SMN2KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL16104919 | 0.78 | LMNA (0.48) | LMNASMN1; SMN2CYP2C19ACHEALDH1A1 | |
| SCHEMBL16104911 | 0.78 | LMNA (0.48) | LMNASMN1; SMN2CYP2C19ACHEALDH1A1 | |
| SCHEMBL16104916 | 0.77 | HPGD (0.46) | LMNASMN1; SMN2CYP2C19ACHEKMT2A | |
| SCHEMBL13347236 | 0.77 | DPP4 (0.53) | LMNAALDH1A1NPC1 | |
| SCHEMBL26673580 | 0.76 | ALDH1A1 (0.49) | LMNASMN1; SMN2CYP2C19KMT2AALDH1A1 | |
| SCHEMBL17346 | 0.75 | L3MBTL1 (0.51) | LMNAACHEALDH1A1L3MBTL1TSHR | |
| SCHEMBL24322557 | 0.74 | ALDH1A1 (0.64) | LMNAKMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL16426 | 0.74 | L3MBTL1 (0.50) | LMNAALDH1A1L3MBTL1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997533-A1 | Heterocyclic boronic acid compounds, dipeptidyl peptidase IV inhibitors | Phenomix Corporation (US) | 2008-12-03 | — | — | EP | disclosed |