Sugi Predict

Sugi Predict / Compounds / SCHEMBL13997802

SCHEMBL13997802

SCHEMBL13997802

CCNc1cc(Cl)nc(Cl)c1[N+](=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PGK1 P00558 1/20 0.44
▸ HCAR3 P49019 1/20 0.38
▸ LMNA P02545 2/20 0.37
▸ MAPT P10636 6/20 0.37
▸ ALDH1A1 P00352 5/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ OPRD1 P41143 1/20 0.35
▸ OPRK1 P41145 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ TLR9 Q9NR96 1/20 0.35
▸ GPR55 Q9Y2T6 1/20 0.35
▸ GAA P10253 2/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3054833 0.82 PGK1 (0.41) PGK1HCAR3LMNAMAPTALDH1A1
SCHEMBL2767459 0.82 MAPT (0.51) PGK1HCAR3LMNAMAPTALDH1A1
SCHEMBL30542027 0.82 MAPT (0.51) PGK1HCAR3LMNAMAPTALDH1A1
SCHEMBL3121902 0.81 PGK1 (0.43) PGK1HCAR3LMNAMAPTALDH1A1
SCHEMBL16486521 0.79 MAPT (0.49) LMNAMAPTALDH1A1SMN1; SMN2MAPK1
SCHEMBL8478082 0.79 KMT2A (0.37) LMNAMAPTALDH1A1MEN1POLB
SCHEMBL5177032 0.78 ALDH1A1 (0.41) MAPTALDH1A1SMN1; SMN2MEN1HTT
SCHEMBL19690963 0.78 GLP1R (0.41) HCAR3LMNAMAPTALDH1A1SMN1; SMN2
SCHEMBL1197137 0.77 ALDH1A1 (0.45) LMNAMAPTALDH1A1SMN1; SMN2POLB
SCHEMBL27638150 0.77 ALDH1A1 (0.40) PGK1HCAR3LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250114345-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS 2025-04-10 — — US disclosed
WO-2025049994-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-03-06 — — WO disclosed
US-20170355708-A1 POTASSIUM CHANNEL MODULATORS CADENT THERAPEUTICS, INC. 2017-12-14 — — US disclosed
US-20170355708-A1 POTASSIUM CHANNEL MODULATORS CADENT THERAPEUTICS, INC. 2017-12-14 — — US disclosed
US-20080318947-A1 Inhibitors of Akt Activity HEERDING DIRK A 2008-12-25 — — US disclosed
US-20080318947-A1 Inhibitors of Akt Activity HEERDING DIRK A 2008-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170355708-A1 POTASSIUM CHANNEL MODULATORS KCNJ11, KCNJ2, KCNJ1 PGK1 775/4885HCAR3 2008/4885LMNA 1523/4885
US-20250114345-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF EP300, CREBBP, HDAC1 PGK1 1472/4885HCAR3 1610/4885LMNA 1583/4885
US-20080318947-A1 Inhibitors of Akt Activity PI4KB, PIK3CA, AKT2 PGK1 355/4885HCAR3 3646/4885LMNA 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.