Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9611280 | 0.84 | RAB9A (0.42) | HTTPKMPOLBMAPTCYP3A4 | |
| Fumaric Acid SCHEMBL1357693 | 0.79 | RAB9A (0.39) | HTTPKMPOLBMAPTSMN1; SMN2 | |
| Fumaric Acid SCHEMBL1357695 | 0.79 | RAB9A (0.39) | HTTPKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL1357880 | 0.79 | HTT (0.44) | HTTPKMPOLBMAPTCYP3A4 | |
| SCHEMBL9611276 | 0.74 | HTR6 (0.38) | MAPTCYP2C19KDM4EALDH1A1 | |
| SCHEMBL13801543 | 0.70 | RAB9A (0.40) | HTTPKMPOLBMAPTKDM4E | |
| Fumaric Acid SCHEMBL3703509 | 0.67 | RAB9A (0.36) | HTTPKMMAPTSMN1; SMN2KMT2A | |
| Fumaric Acid SCHEMBL3703504 | 0.67 | RAB9A (0.36) | HTTPKMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL1156298 | 0.66 | HTT (0.44) | HTTPKMPOLBMAPTCYP3A4 | |
| SCHEMBL1156990 | 0.64 | HTT (0.42) | HTTPKMPOLBMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2005957-A1 | ACID SECRETION INHIBITOR | Takeda Pharmaceutical Company Limited (JP) | 2008-12-24 | — | — | EP | disclosed |