Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 19/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128288 | 0.91 | MLNR (0.46) | MLNRCYP3A4CYP2D6GHSRS1PR1 | |
| SCHEMBL5129137 | 0.88 | KDM4E (0.44) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL4790020 | 0.81 | MLNR (0.44) | MLNRCYP3A4S1PR1S1PR5 | |
| SCHEMBL4701395 | 0.79 | MLNR (0.69) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL5132190 | 0.77 | MLNR (0.39) | MLNRCYP3A4 | |
| SCHEMBL5132518 | 0.77 | MLNR (0.70) | MLNRCYP3A4CYP2D6GHSR | |
| SCHEMBL2326438 | 0.75 | HRH3 (0.49) | MLNRCYP3A4 | |
| SCHEMBL2326434 | 0.75 | HRH3 (0.49) | MLNRCYP3A4 | |
| SCHEMBL14001065 | 0.73 | MLNR (0.53) | MLNRCYP3A4 | |
| Hydrochloric Acid SCHEMBL5129748 | 0.72 | MLNR (0.53) | MLNRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312209-A1 | Piperazine Heteroaryl Derivatives as Gpr38 Agonists | GLAXO GROUP LIMITED | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312209-A1 | Piperazine Heteroaryl Derivatives as Gpr38 Agonists | GPR68, GPR55, GPR88 | MLNR 207/4885CYP3A4 784/4885CYP2D6 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.