Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16926353 | 0.85 | OPRM1 (0.51) | OPRM1OPRK1SIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL16915737 | 0.85 | OPRM1 (0.51) | OPRM1OPRK1SIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL29710109 | 0.85 | OPRM1 (0.51) | OPRM1OPRK1SIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL16915579 | 0.85 | OPRM1 (0.51) | OPRM1OPRK1SIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL20473610 | 0.85 | OPRM1 (0.51) | OPRM1OPRK1SIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL16926718 | 0.85 | OPRM1 (0.51) | OPRM1OPRK1SIGMAR1CYP3A4HSD17B10 | |
| SCHEMBL12265181 | 0.81 | OPRM1 (0.57) | OPRM1OPRK1SIGMAR1ACHECYP3A4 | |
| SCHEMBL29312728 | 0.81 | OPRM1 (0.53) | OPRM1OPRK1SIGMAR1ACHECYP3A4 | |
| SCHEMBL11401193 | 0.77 | OPRM1 (0.69) | OPRM1OPRK1 | |
| SCHEMBL22528005 | 0.77 | ACHE (0.50) | OPRM1OPRK1SIGMAR1ACHECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319020-A1 | 4-Oxadiazolyl-Piperidine Compounds and Use Thereof | PURDUE PHARMA L.P. | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319020-A1 | 4-Oxadiazolyl-Piperidine Compounds and Use Thereof | VIP, ALPI, OPRD1 | OPRM1 7/4885OPRK1 4/4885SIGMAR1 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.