Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070872 | 0.86 | AKR1C3 (0.55) | ALDH1A1TSHRAKR1C3RECQLMAPT | |
| SCHEMBL13879068 | 0.86 | AKR1C3 (0.55) | ALDH1A1TSHRAKR1C3RECQLMAPT | |
| SCHEMBL14003229 | 0.84 | RECQL (0.55) | ALDH1A1TSHRAKR1C3RECQLMAPT | |
| SCHEMBL14003231 | 0.84 | RECQL (0.55) | ALDH1A1TSHRAKR1C3RECQLMAPT | |
| SCHEMBL22263074 | 0.83 | KMT2A (0.59) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL22263078 | 0.83 | KMT2A (0.59) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL20610671 | 0.82 | MCL1 (0.49) | ALDH1A1TSHRAKR1C3RECQLMAPT | |
| SCHEMBL976606 | 0.80 | AKR1C3 (0.64) | ALDH1A1TSHRAKR1C3RECQLMAPT | |
| SCHEMBL976605 | 0.80 | AKR1C3 (0.64) | ALDH1A1TSHRAKR1C3RECQLMAPT | |
| SCHEMBL27542414 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRAKR1C3RECQLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851086-B2 | Polycrystalline form of dehydrophenylahistin-like compound, and manufacturing and purification method and application thereof | MARINE BIOMEDICAL RESEARCH INSTITUTE OF QINGDAO CO., LTD. (CN) | 2020-12-01 | — | — | US | disclosed |
| US-20190177302-A1 | POLYCRYSTALLINE FORM OF DEHYDROPHENYLAHISTIN-LIKE COMPOUND, AND MANUFACTURING AND PURIFICATION METHOD AND APPLICATION THEREOF | SHENZHEN HUAHONG MARINE BIOMEDICINE CO., LTD (CN) | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851086-B2 | Polycrystalline form of dehydrophenylahistin-like compound, and manufacturing and purification method and application thereof | DHPS, HDHD5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALDH1A1 3153/4885TSHR 964/4885AKR1C3 2709/4885 |
| US-20190177302-A1 | POLYCRYSTALLINE FORM OF DEHYDROPHENYLAHISTIN-LIKE COMPOUND, AND MANUFACTURING AND PURIFICATION METHOD AND APPLICATION THEREOF | DHPS, HDHD5, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALDH1A1 3153/4885TSHR 964/4885AKR1C3 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.