SCHEMBL14004340

SCHEMBL14004340

C=CS(=O)(=O)CCNc1nc(NCCOS(=O)(=O)O)c(/N=N/c2ccc(/C=C/c3ccc(/N=N/c4c(NCCS(=O)(=O)C=C)nc(NCCOS(=O)(=O)O)c(C#N)c4C)cc3S(=O)(=O)O)c(S(=O)(=O)O)c2)c(C)c1C#N

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 5/20 0.36
▸ SENP1 Q9P0U3 5/20 0.36
▸ SENP3 Q9H4L4 4/20 0.36
▸ SUMO2 P61956 3/20 0.36
▸ SUMO1 P63165 3/20 0.36
▸ SENP7 Q9BQF6 3/20 0.36
▸ RAD1 O60671 1/20 0.33
▸ P2RY6 Q15077 1/20 0.33
▸ MAPT P10636 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14004348 1.00 SENP2 (0.36) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL14004343 1.00 SENP2 (0.36) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL14004333 0.92 MAPT (0.31) MAPTTDP1
SCHEMBL14004342 0.92 MAPT (0.31) MAPTTDP1
SCHEMBL14004339 0.92 MAPT (0.31) MAPTTDP1
SCHEMBL14029354 0.88 MAPK8 (0.30) —
SCHEMBL14029351 0.88 MAPK8 (0.30) —
SCHEMBL14004298 0.88 CD40 (0.38) MAPTTDP1
SCHEMBL14004327 0.88 ATIC (0.37) SENP2SUMO2SUMO1SENP7
SCHEMBL14004329 0.88 ATIC (0.37) SENP2SUMO2SUMO1SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080289124-A1 Reactive Azo Dyes, Methods for the Production Thereof and Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-11-27 — — US disclosed
US-20080289124-A1 Reactive Azo Dyes, Methods for the Production Thereof and Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-11-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080289124-A1 Reactive Azo Dyes, Methods for the Production Thereof and Their Use IK, CYP1A1, ALKBH1 SENP2 3998/4885SENP1 3063/4885SENP3 3987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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