Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | PRKCG | P05129 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14004681 | 0.95 | HDAC6 (0.66) | HDAC1HDAC6HDAC2HDAC8PTGS2 | |
| SCHEMBL11900090 | 0.85 | HDAC6 (0.85) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL457082 | 0.85 | HDAC6 (0.79) | HDAC1HDAC6HDAC2HDAC8HPGD | |
| SCHEMBL6843720 | 0.83 | HDAC6 (0.77) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| Hydrochloric Acid SCHEMBL3757721 | 0.83 | HDAC6 (0.76) | HDAC1HDAC6HDAC2HDAC8HPGD | |
| SCHEMBL29184442 | 0.83 | HDAC6 (0.76) | HDAC1HDAC6HDAC2HDAC8HPGD | |
| SCHEMBL4749020 | 0.83 | HDAC6 (0.66) | HDAC1HDAC6HDAC2HDAC8PTGS2 | |
| SCHEMBL2924662 | 0.82 | HDAC6 (0.74) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL28966141 | 0.81 | HDAC1 (1.00) | HDAC1HDAC6HDAC2HDAC8HDAC3 | |
| SCHEMBL17744942 | 0.81 | HDAC6 (0.68) | HDAC1HDAC6HDAC2HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | HDAC1 803/4885HDAC6 1039/4885HDAC2 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.