Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14433146 | 0.93 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL2822780 | 0.86 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL23659151 | 0.82 | MEN1 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3MEN1 | |
| SCHEMBL22098728 | 0.82 | MEN1 (0.42) | CHRNB2CHRNA4CHRNB4CHRNA3MEN1 | |
| SCHEMBL13448559 | 0.80 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3CHRM2 | |
| SCHEMBL14005100 | 0.80 | CA12 (0.41) | CHRNB2CHRNA4TSHRALDH1A1TP53 | |
| SCHEMBL16172020 | 0.78 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL10619053 | 0.77 | MEN1 (0.46) | MEN1KMT2ATSHRALDH1A1MAPK1 | |
| SCHEMBL24092261 | 0.75 | MEN1 (0.37) | CHRNB2CHRNA4MEN1KMT2ATSHR | |
| SCHEMBL14005163 | 0.75 | CA12 (0.38) | CHRNB2CHRNA4MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053191-B2 | Hydroxy functional alkyl carbamate crosslinkers | PPG INDUSTRIES OHIO, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| US-20190210962-A1 | HYDROXY FUNCTIONAL ALKYL CARBAMATE CROSSLINKERS | PPG INDUSTRIES OHIO, INC. | 2019-07-11 | — | — | US | disclosed |
| US-20080293660-A1 | CHEMICALLY-DEFINED NON-POLYMERIC VALENCY PLATFORM MOLECULES AND CONJUGATES THEREOF | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-11-27 | — | — | US | disclosed |
| US-7351855-B2 | Chemically defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| US-20070254851-A1 | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293660-A1 | CHEMICALLY-DEFINED NON-POLYMERIC VALENCY PLATFORM MOLECULES AND CONJUGATES THEREOF | SSB, PCNA, NCL | CHRNB2 4396/4885CHRNA4 4478/4885CHRNB4 4340/4885 |
| US-20190210962-A1 | HYDROXY FUNCTIONAL ALKYL CARBAMATE CROSSLINKERS | C9, JMJD6, CBR3 | CHRNB2 2029/4885CHRNA4 1656/4885CHRNB4 1977/4885 |
| US-11053191-B2 | Hydroxy functional alkyl carbamate crosslinkers | C9, JMJD6, CBR3 | CHRNB2 2029/4885CHRNA4 1656/4885CHRNB4 1977/4885 |
| US-20070254851-A1 | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | SSB, PCNA, NCL | CHRNB2 4396/4885CHRNA4 4478/4885CHRNB4 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.