Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14005978 | 0.88 | CHRNA7 (0.62) | ALDH1A1CHRNA7POLB | |
| SCHEMBL14006035 | 0.88 | CACNA1G (0.49) | ALDH1A1 | |
| SCHEMBL14006101 | 0.87 | CHRNA7 (0.60) | ALDH1A1CHRNA7POLB | |
| SCHEMBL14006028 | 0.86 | CHRNA7 (0.53) | ALDH1A1CHRNA7POLBIKBKBCHUK | |
| SCHEMBL14006217 | 0.85 | CHRNA3 (0.64) | — | |
| SCHEMBL14006214 | 0.85 | CHRNA7 (0.51) | ALDH1A1CHRNA7POLBIKBKBCHUK | |
| SCHEMBL14006213 | 0.84 | MAPK1 (0.53) | ALDH1A1CHRNA7SMN1; SMN2 | |
| SCHEMBL14005927 | 0.83 | ALDH1A1 (0.81) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14005911 | 0.82 | CHRNA7 (0.57) | ALDH1A1CHRNA7POLBSMN1; SMN2 | |
| SCHEMBL14006005 | 0.82 | CHRNA7 (0.57) | ALDH1A1CHRNA7POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | CHRNA7, CHRNA5, CHRNA1 | ALDH1A1 2091/4885CHRNA7 1/4885POLB 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.