Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22521943 | 0.82 | CYP2C9 (0.49) | ADORA2BPOLBMAPTALDH1A1HSD17B10 | |
| SCHEMBL461786 | 0.79 | PDE2A (0.62) | ADORA2BPOLBALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL3194191 | 0.78 | ADORA2A (0.59) | ADORA2BPOLBALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL515792 | 0.78 | POLB (0.57) | ADORA2BPOLBALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL9122777 | 0.78 | ALDH1A1 (0.59) | ADORA2BPOLBMAPTALDH1A1HSD17B10 | |
| 8-Chlorotheophylline SCHEMBL411139 | 0.78 | POLB (0.57) | ADORA2BPOLBMAPTALDH1A1HSD17B10 | |
| SCHEMBL20783386 | 0.78 | POLB (0.57) | ADORA2BPOLBMAPTALDH1A1HSD17B10 | |
| Pamabrom SCHEMBL237881 | 0.78 | POLB (0.61) | ADORA2BPOLBALDH1A1HSD17B10CYP3A4 | |
| Water SCHEMBL28799658 | 0.78 | PDE2A (0.60) | ADORA2BPOLBALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL11185440 | 0.78 | POLB (0.57) | ADORA2BPOLBMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1374308-A | Antineoplastic active compound nitrene-phin and its prepn | MILITARY MEDICAL UNIV NO 2 PLA (CN) | 2002-10-16 | — | — | CN | claimed |
| US-4073908-A | PSYCHOTROPIC ACTIVITY | LABORATOIRE LE BRUN S.A. (FR) | 1978-02-14 | — | — | US | claimed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| WO-2020205646-A2 | SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-10-08 | — | — | WO | disclosed |
| US-20200278346-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ADJACENT ACQUISITION CO., LLC | 2020-09-03 | — | — | US | disclosed |
| EP-3681504-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | Icagen, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| EP-0077896-B1 | THEOPHYLLINE DERIVATIVES, ANTIBODIES AND THEIR PREPARATION FROM THEOPHYLLINE IMMUNOGENS, AS WELL AS AN IMMUNO ASSAY METHOD AND REAGENT MEANS FOR DETERMINING THEOPHYLLINE | MILES INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4655767-A | REDUCED SENSITIVITY TO AMINO-FUNCTIONAL DRUGS | DOW CORNING CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |
| US-4608336-A | DETERMINATION OF THEOPHYLLINE IN BIOLOGICAL FLUIDS | MILES LABORATORIES, INC. (US) | 1986-08-26 | — | — | US | disclosed |
| US-4533493-A | IMMUNOASSAYS FOR MEASUREMENT OF THEOPHYLLINE IN BIOLOGIACAL FLUIDS | MILES LABORATORIES, INC. (US) | 1985-08-06 | — | — | US | disclosed |
| US-4460772-A | IMMUNOASSAY | MILES LABORATORIES, INC. (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0077896-A1 | Theophylline derivatives, antibodies and their preparation from theophylline immunogens, as well as an immuno assay method and reagent means for determining theophylline | MILES INC. (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4073908-A | PSYCHOTROPIC ACTIVITY | LABORATOIRE LE BRUN S.A. (FR) | 1978-02-14 | — | — | US | disclosed |
| US-4073908-A | PSYCHOTROPIC ACTIVITY | LABORATOIRE LE BRUN S.A. (FR) | 1978-02-14 | — | — | US | disclosed |
| US-4073908-A | PSYCHOTROPIC ACTIVITY | LABORATOIRE LE BRUN S.A. (FR) | 1978-02-14 | — | — | US | disclosed |