Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.62 |
| ▸ | PDE1A | P54750 | 1/20 | 0.62 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.62 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28799658 | 0.98 | PDE2A (0.60) | PDE2APDE1APDE1BPDE1CPOLB | |
| Caffeine SCHEMBL2327080 | 0.84 | ADORA2A (0.68) | PDE2APDE1APDE1BPDE1CPOLB | |
| SCHEMBL7093373 | 0.81 | CYP2C9 (0.50) | PDE2APDE1APDE1BPDE1CPOLB | |
| SCHEMBL515533 | 0.81 | CYP3A4 (0.62) | PDE2APDE1APDE1BPDE1CPOLB | |
| SCHEMBL7017824 | 0.81 | PDE2A (0.58) | PDE2APDE1APDE1BPDE1CPOLB | |
| SCHEMBL25249437 | 0.80 | PDE1A (0.69) | PDE2APDE1APDE1BPDE1CPOLB | |
| Pamabrom SCHEMBL237881 | 0.79 | POLB (0.61) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| 8-Chlorotheophylline SCHEMBL411139 | 0.79 | POLB (0.57) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL1400610 | 0.79 | ADORA2B (0.57) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL20783386 | 0.79 | POLB (0.57) | POLBHSD17B10ALDH1A1CYP3A4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294421-B1 | METHOD FOR COSMETIC TREATMENT OF THE SKIN | CHA LING (FR) | 2021-08-11 | — | — | EP | claimed |
| US-20190046471-A1 | Methods and Compositions for the Treatment of Steatosis-Associated Disorders | DUKE UNIVERSITY | 2019-02-14 | — | — | US | claimed |
| CN-108430450-A | Method for dermocosmesis treatment | 茶灵 | 2018-08-21 | — | — | CN | claimed |
| EP-3294421-A1 | METHOD FOR COSMETIC TREATMENT OF THE SKIN | Cha, Ling (FR) | 2018-03-21 | — | — | EP | claimed |
| WO-2017049157-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF STEATOSIS-ASSOCIATED DISORDERS | DUKE UNIVERSITY (US) | 2017-03-23 | — | — | WO | claimed |
| WO-2016181086-A1 | METHOD FOR COSMETIC TREATMENT OF THE SKIN | CHA LING (FR) | 2016-11-17 | — | — | WO | claimed |
| CN-103837612-B | Method for measuring related substances of doxofylline injection | 黑龙江福和华星制药集团股份有限公司 | 2016-10-05 | — | — | CN | claimed |
| CN-105660906-A | Functional health-care drink composition with effect of reducing blood fat and application thereof | 中国土产畜产进出口总公司 | 2016-06-15 | — | — | CN | claimed |
| CN-105638937-A | Black tea processing method | 镇江市五峰茶场 | 2016-06-08 | — | — | CN | claimed |
| CN-105505957-A | Specific primer pair, allele and molecular marker for screening thea section with low caffeine trait and screening method | TEA RES INST CAAS | 2016-04-20 | — | — | CN | claimed |
| CN-1087893-A | The comprehensive technology of extracting tea-polyphenol trimethyl-xanthine phyllochlorin matter from tealeaves | UNIV SICHUAN AGRICULTURAL (CN) | 1994-06-15 | — | — | CN | claimed |
| CN-1068111-A | (mixing) aryl oxide and sulfide derivative, its preparation method and pharmaceutical composition | PERREL S P A (IT) | 1993-01-20 | — | — | CN | claimed |
| EP-0167566-A4 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | SUNSHINE ABRAHAM (US) | 1987-06-29 | — | — | EP | claimed |
| EP-0165308-A4 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | RICHARDSON VICKS INC (US) | 1986-05-16 | — | — | EP | claimed |
| US-4567183-A | SYNERGISTIC, POTENTIATION | ANALGESIC ASSOCIATES (US) | 1986-01-28 | — | — | US | claimed |
| EP-0167566-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | SUNSHINE, Abraham (US) | 1986-01-15 | — | — | EP | claimed |
| EP-0165308-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. | RICHARDSON VICKS INC (US) | 1985-12-27 | — | — | EP | claimed |
| US-4558051-A | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same | RICHARDSON-VICKS, INC. (US) | 1985-12-10 | — | — | US | claimed |
| WO-1985002540-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | RICHARDSON-VICKS, INC. (US) | 1985-06-20 | — | — | WO | claimed |
| WO-1985002542-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME | SUNSHINE ABRAHAM | 1985-06-20 | — | — | WO | claimed |