Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461786 | 0.79 | PDE2A (0.62) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL515792 | 0.78 | POLB (0.57) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| 8-Chlorotheophylline SCHEMBL411139 | 0.78 | POLB (0.57) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL11185440 | 0.78 | POLB (0.57) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL1400610 | 0.78 | ADORA2B (0.57) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL9122777 | 0.78 | ALDH1A1 (0.59) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| SCHEMBL3194191 | 0.78 | ADORA2A (0.59) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| Pamabrom SCHEMBL237881 | 0.78 | POLB (0.61) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| Water SCHEMBL28799658 | 0.78 | PDE2A (0.60) | POLBHSD17B10ALDH1A1CYP3A4CASP1 | |
| 8-Chlorotheophylline SCHEMBL5719335 | 0.76 | POLB (0.55) | POLBHSD17B10ALDH1A1CYP3A4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070184-A1 | DEUTERATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING CARDIOVASCULAR DISEASES | Cardix Therapeutics LLC (US) | 2019-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190070184-A1 | DEUTERATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF TREATING CARDIOVASCULAR DISEASES | ADRB2, ADRA2C, ADRB1 | POLB 1527/4885HSD17B10 1263/4885ALDH1A1 1867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.