SCHEMBL1400620

SCHEMBL1400620

CCCc1c(O)cccc1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
CYP3A4 P08684 1/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
MAPK1 P28482 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
TSHR P16473 1/20 0.52
ALOX5 P09917 2/20 0.49
PTGS2 P35354 1/20 0.49
HMGCR P04035 1/20 0.47
ELANE P08246 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31613792 1.00 TP53 (0.55) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL31327375 0.89 ALOX5 (0.54) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL59744 0.89 ALOX5 (0.54) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL7210174 0.87 ALOX5 (0.53) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL7044011 0.87 ALOX5 (0.61) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL27894235 0.86 ALOX5 (0.59) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL8564056 0.86 CA1 (0.48) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL544792 0.85 TP53 (0.55) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL6468612 0.84 TP53 (0.59) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL23143319 0.83 ALOX5 (0.49) TP53KDM4EALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555921-B The method and system of supply hydrogen is reacted to hydrogenation catalyst 国际壳牌研究有限公司 2018-05-22 CN claimed
US-9080109-B2 Methods for deoxygenating biomass-derived pyrolysis oil UOP LLC (US) 2015-07-14 US claimed
EP-2791283-A1 METHODS FOR DEOXYGENATING BIOMASS-DERIVED PYROLYSIS OIL UOP LLC (US) 2014-10-22 EP claimed
WO-2013089838-A1 METHODS FOR DEOXYGENATING BIOMASS-DERIVED PYROLYSIS OIL UOP LLC (US) 2013-06-20 WO claimed
US-20130158329-A1 METHODS FOR DEOXYGENATING BIOMASS-DERIVED PYROLYSIS OIL UOP LLC (US) 2013-06-20 US claimed
WO-2024030611-A2 CONTINUOUS HYDRODEOXYGENATION OF LIGNIN TO JET-RANGE AROMATIC HYDROCARBONS ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2024-02-08 WO disclosed
CN-107735482-B The biomass conversion process of single oxidation stream is obtained using amorphous silicon aluminum oxide 国际壳牌研究有限公司 2019-11-05 CN disclosed
EP-3046993-B1 METHODS AND SYSTEMS FOR SUPPLYING HYDROGEN TO A HYDROCATALYTIC REACTION SHELL INT RESEARCH (NL) 2018-08-22 EP disclosed
CN-105555921-B The method and system of supply hydrogen is reacted to hydrogenation catalyst 国际壳牌研究有限公司 2018-05-22 CN disclosed
CN-107849464-A The biomass conversion process of single oxidation stream is obtained using amorphous silicon aluminum oxide 国际壳牌研究有限公司 2018-03-27 CN disclosed
CN-107801400-A Biomass conversion process using amorphous silica alumina to obtain a mono-oxidized stream 国际壳牌研究有限公司 2018-03-13 CN disclosed
CN-107735482-A The biomass conversion process of single oxidation stream is obtained using amorphous silicon aluminum oxide 国际壳牌研究有限公司 2018-02-23 CN disclosed
US-6489365-B1 LTB4-ANTAGONISTIC COMPOUNDS FOR TREATMENT OF INFLAMMATION, ALLERGY OR GASTROPATHY INDUCED BY NON-STEROIDAL ANTIINFLAMMATORY AGENTS IN A WARM-BLOODED ANIMALS BOEHRINGER INGELHEIM KG (DE) 2002-12-03 US disclosed
EP-0902013-B1 Novel amidine derivatives, their preparation and their use as medicaments with LTB-4 antagonistic effect BOEHRINGER INGELHEIM INT (DE) 2001-12-12 EP disclosed
US-6037377-A ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS BOEHRINGER INGELHEIM KG (DE) 2000-03-14 US disclosed
EP-0902013-A1 Novel amidine derivatives, their preparation and their use as medicaments with LTB-4 antagonistic effect BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1999-03-17 EP disclosed
EP-0544488-B1 Substituted phenyl phenol leukotriene antagonists LILLY CO ELI (US) 1998-03-11 EP disclosed
EP-0625138-A1 NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDIAMENTS WITH LTB-4 ANTAGONISTIC EFFECT BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1994-11-23 EP disclosed
WO-1993016036-A1 NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDIAMENTS WITH LTB-4 ANTAGONISTIC EFFECT BOEHRINGER INGELHEIM KG (DE) 1993-08-19 WO disclosed
EP-0544488-A2 Substituted phenyl phenol leukotriene antagonists ELI LILLY AND COMPANY (US) 1993-06-02 EP disclosed