SCHEMBL6468612

SCHEMBL6468612

CCc1c(O)cccc1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.59
KDM4E B2RXH2 2/20 0.59
ALDH1A1 P00352 1/20 0.59
LMNA P02545 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAPT P10636 1/20 0.59
HPGD P15428 1/20 0.59
ALOX15 P16050 1/20 0.59
ALOX12 P18054 1/20 0.59
MAPK1 P28482 1/20 0.59
HSD17B10 Q99714 1/20 0.59
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
TSHR P16473 1/20 0.56
RET P07949 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALOX5 P09917 1/20 0.43
PTGS2 P35354 1/20 0.43
BCHE P06276 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27851131 0.98 TP53 (0.57) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL1547302 0.84 CA1 (0.52) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL31613792 0.84 TP53 (0.55) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL1400620 0.84 TP53 (0.55) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL11358137 0.83 TP53 (0.59) TP53KDM4EALDH1A1LMNACYP3A4
Methoxymethane SCHEMBL11436648 0.82 LMNA (0.44) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL11776675 0.82 MAPT (0.44) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL5220560 0.82 LMNA (0.57) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL5010803 0.82 TP53 (0.57) TP53KDM4EALDH1A1LMNACYP3A4
SCHEMBL31327375 0.81 ALOX5 (0.54) TP53KDM4EALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110178962-A The purposes of the clam active polypeptide of ultrasonic wave extraction 兰溪市哥特生物技术有限公司 2019-08-30 CN claimed
CN-208694284-U A kind of high-quality is to methoxy ethyl phenol rectification tower 如皋市众昌化工有限公司 2019-04-05 CN claimed
CN-108689810-A To the synthetic method of methoxy ethyl phenol 连云港市工投集团利海化工有限公司 2018-10-23 CN claimed
CN-103980134-B A kind of preparation method of succsinic acid S-metoprolol XINXING MEDICAMENT DEVELOPMENT CO., LTD., ANHUI PROV. (CN) 2015-09-30 CN claimed
CN-102381995-B Preparation method of metoprolol YANGTZE RIVER PHARMACEUTICAL GROUP BEIJING HAIYAN PHARMACEUTICAL CO LTD 2015-04-15 CN claimed
CN-103980134-A Preparation method of succinic acid S-metoprolol ANHUI NEW STAR PHARMACEUTICAL DEV CO LTD 2014-08-13 CN claimed
CN-102633660-A New crystal form of metoprolol succinate BEIJING HUAXI LIANHE TECHNOLOGY DEV CO LTD 2012-08-15 CN claimed
CN-102432476-A Method for preparing metoprolol succinate on scale HUNAN KAMP INST FOR MEDICAL RES 2012-05-02 CN claimed
CN-102381995-A Preparation method of metoprolol YANGZIJIANG PHARMACEUTICAL GROUP BEIJING PETREL PHARMACEUTICAL CO LTD 2012-03-21 CN claimed
CN-120664951-B Deprotection method of p-tert-butoxyphenethyl methyl ether 山东普洛汉兴医药有限公司 2025-12-26 CN disclosed
CN-120664951-A Deprotection method of p-tert-butoxyphenethyl methyl ether 山东普洛汉兴医药有限公司 2025-09-19 CN disclosed
CN-116020438-B Solid acid catalyst, preparation method thereof and application of solid acid catalyst in deprotection reaction of p-tert-butoxyphenethyl methyl ether 山东普洛汉兴医药有限公司 2024-08-02 CN disclosed
US-11840550-B2 Silyl-biaryl phosphoramidites and methods of making BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-12-12 US disclosed
US-20230203060-A1 FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) 2023-06-29 US disclosed
CN-102381995-A Preparation method of metoprolol YANGZIJIANG PHARMACEUTICAL GROUP BEIJING PETREL PHARMACEUTICAL CO LTD 2012-03-21 CN disclosed
CN-1922104-A Metal oxide particle and its use NIPPON CATALYTIC CHEM IND (JP) 2007-02-28 CN disclosed
CN-1286883-C Polymerizable composition containing novel cyclic sulfur compound and resin obtained by curing the polymerizable composition MITSUI CHEMICALS INC (JP) 2006-11-29 CN disclosed
CN-1678521-A Compound semiconductor particles and production process therefor MASAKAZU KOBAYASHI (JP) 2005-10-05 CN disclosed
CN-1596276-A Polymerizable composition comprising novel sulfur-containing cyclic compound and resin obtained by curing the polymerizable composition MITSUI CHEMICALS INC (JP) 2005-03-16 CN disclosed
CN-1042153-A 3-aryloxy methyl-cephalosporins derivatives, their preparation and purposes pharmaceutically SANKYO CO (JP) 1990-05-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840550-B2 Silyl-biaryl phosphoramidites and methods of making PAICS, PGLS, SCLY TP53 2492/4885KDM4E 3107/4885ALDH1A1 3857/4885
US-20230203060-A1 FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF KRAS, NRAS, TP53 TP53 3/4885KDM4E 4302/4885ALDH1A1 3223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.