SCHEMBL544792

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5782701	0.88	TP53 (0.46)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL31613792	0.85	TP53 (0.55)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL1400620	0.85	TP53 (0.55)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL11358137	0.84	TP53 (0.59)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL10059970	0.83	MAPT (0.53)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL3696213	0.83	TSHR (0.55)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL31327375	0.81	ALOX5 (0.54)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL59744	0.81	ALOX5 (0.54)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL506887	0.81	ALOX5 (0.45)	TP53MAPTKDM4EALDH1A1LMNA
	SCHEMBL7210174	0.80	ALOX5 (0.53)	TP53MAPTKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.