Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632076 | 0.83 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL10069472 | 0.81 | KMT2A (0.83) | NPC1RAB9ASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL7162285 | 0.81 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL10055020 | 0.80 | NPC1 (0.94) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL24711194 | 0.78 | KMT2A (0.71) | NPC1RAB9ASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL4256368 | 0.78 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL94789 | 0.77 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4251080 | 0.77 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL4252397 | 0.75 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL31179863 | 0.75 | NPC1 (0.83) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293739-A1 | COMPOUNDS FOR MODULATING T-CELLS | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293739-A1 | COMPOUNDS FOR MODULATING T-CELLS | CD4, HLA-DRB1, CD74 | NPC1 4379/4885RAB9A 2276/4885SMN1; SMN2 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.