Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
| ▸ | BRD2 | P25440 | 2/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14007199 | 0.85 | BRD4 (0.45) | MLYCDBRD4BRD2BRD3BRDT | |
| SCHEMBL13702154 | 0.85 | BRD4 (0.45) | MLYCDBRD4BRD2BRD3BRDT | |
| SCHEMBL14007191 | 0.84 | ALDH1A1 (0.49) | MLYCDBRD4BRD2BRD3BRDT | |
| SCHEMBL13702146 | 0.83 | KDM4E (0.44) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL13702123 | 0.83 | EPHX2 (0.64) | MLYCDBRD4BRD2BRD3BRDT | |
| SCHEMBL13702165 | 0.82 | BRD4 (0.49) | MLYCDBRD4BRD2BRD3BRDT | |
| SCHEMBL13702181 | 0.81 | LMNA (0.43) | MLYCDBRD4BRD2BRD3BRDT | |
| SCHEMBL13702152 | 0.81 | BRD4 (0.73) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL13702178 | 0.81 | HRH3 (0.51) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL13702175 | 0.81 | EPHX2 (0.45) | MLYCDBRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280904-A1 | N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors | ELDRUP ANNE BETTINA | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280904-A1 | N-Substituted Pyridinone or Pyrimidinone Compounds Useful as Soluble Epoxide Hydrolase Inhibitors | EPHX1, EPHX2, DOHH | MLYCD 3655/4885BRD4 2988/4885BRD2 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.