Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961977 | 0.86 | GABRA1 (0.50) | GABRA1GABRB2LMNAALDH1A1FLT1 | |
| SCHEMBL8093673 | 0.84 | GABRA1 (0.48) | GABRA1GABRB2LMNAALDH1A1FLT1 | |
| SCHEMBL27534371 | 0.82 | CYP2A6 (0.38) | GABRA1GABRB2LMNAALDH1A1SLC6A4 | |
| SCHEMBL7819545 | 0.82 | GABRA1 (0.34) | GABRA1GABRB2LMNAALDH1A1SLC6A4 | |
| SCHEMBL17009987 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2LMNAALDH1A1SLC6A4 | |
| SCHEMBL332762 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2LMNAALDH1A1SLC6A4 | |
| SCHEMBL11512007 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2LMNAALDH1A1SLC6A4 | |
| SCHEMBL7112459 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2LMNAALDH1A1SLC6A4 | |
| SCHEMBL16041220 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2LMNAALDH1A1HTR2A | |
| SCHEMBL1457266 | 0.76 | ALDH1A1 (0.42) | GABRA1GABRB2LMNAALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456170-B2 | Triazolobenzodiazepines and their use as vasopressin antagonists | PFIZER INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070249585-A1 | Triazolobenzodiazepines and Their Use as Vasopressin Antagonists | PFIZER INC. | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249585-A1 | Triazolobenzodiazepines and Their Use as Vasopressin Antagonists | AVPR2, AVPR1A, AVPR1B | GABRA1 921/4885GABRB2 1479/4885LMNA 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.