Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 4/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.35 |
| ▸ | CHAT | P28329 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592014 | 0.86 | PLCD1 (0.44) | — | |
| SCHEMBL23346363 | 0.85 | POLG (0.45) | — | |
| SCHEMBL22858568 | 0.84 | P2RX3 (0.42) | P2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL21191413 | 0.84 | P2RX3 (0.42) | P2RX3P2RX1P2RX2P2RX4 | |
| SCHEMBL20417316 | 0.84 | POLB (0.42) | AURKAP2RX3EP300P2RX1P2RX2 | |
| SCHEMBL20417307 | 0.84 | POLB (0.42) | AURKAP2RX3EP300P2RX1P2RX2 | |
| SCHEMBL16152183 | 0.83 | POLB (0.46) | P2RX3P2RX1P2RX2CA2 | |
| SCHEMBL13654889 | 0.82 | NAA50 (0.33) | AURKAEP300CHATKAT5NAA50 | |
| SCHEMBL13670363 | 0.81 | P2RX3 (0.36) | P2RX3P2RX1P2RX2CHATP2RX4 | |
| SCHEMBL23346380 | 0.81 | POLB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452698-B2 | Terminal phosphate blocked nucleoside polyphosphates | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2008-11-18 | — | — | US | disclosed |
| US-20070292879-A1 | TERMINAL PHOSPHATE BLOCKED NUCLEOSIDE POLYPHOSPHATES | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-12-20 | — | — | US | disclosed |
| US-7256019-B2 | Terminal phosphate blocked nucleoside polyphosphates | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-08-14 | — | — | US | disclosed |