Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCD1 | P51178 | 1/20 | 0.44 |
| ▸ | HLCS | P50747 | 3/20 | 0.44 |
| ▸ | HINT1 | P49773 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982838 | 0.91 | HLCS (0.49) | PLCD1HLCSHINT1F2 | |
| SCHEMBL30763662 | 0.90 | PLCD1 (0.44) | PLCD1HLCSTDP1F2PRSS1 | |
| SCHEMBL23346420 | 0.88 | KDM4E (0.37) | PLCD1HLCSBTKPRKAA2 | |
| SCHEMBL22192980 | 0.88 | HLCS (0.46) | PLCD1HLCSHINT1TDP1F2 | |
| SCHEMBL30479095 | 0.87 | PLCD1 (0.47) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL14009653 | 0.86 | PRKACA (0.39) | — | |
| SCHEMBL22897369 | 0.83 | HLCS (0.47) | PLCD1HLCSHINT1F2 | |
| SCHEMBL19983263 | 0.82 | PLCD1 (0.43) | PLCD1HLCSTDP1F2PRSS1 | |
| SCHEMBL20129500 | 0.81 | F2 (0.47) | PLCD1HLCSTDP1F2 | |
| SCHEMBL20126980 | 0.81 | F2 (0.47) | PLCD1HLCSTDP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225941-A1 | IMPROVEMENTS TO REACTIONS WITH NON-RETROVIRAL REVERSE TRANSCRIPTASE | The Regents of the University of California (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076759-A1 | IMPROVEMENTS TO REACTIONS WITH NON-RETROVIRAL REVERSE TRANSCRIPTASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-14 | — | — | WO | disclosed |