Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447489 | 0.81 | GSK3B (0.39) | HTTALDH1A1GSK3BDYRK1AWNT1 | |
| SCHEMBL28442548 | 0.81 | HTT (0.62) | HTTALDH1A1KMT2AGSK3BDYRK1A | |
| SCHEMBL28456680 | 0.81 | GSK3B (0.39) | HTTALDH1A1GSK3BDYRK1AWNT1 | |
| SCHEMBL28444960 | 0.81 | GSK3B (0.39) | HTTALDH1A1GSK3BDYRK1AWNT1 | |
| SCHEMBL22078923 | 0.80 | HDAC8 (0.54) | MKNK1HDAC3HDAC1HDAC2HTT | |
| SCHEMBL761339 | 0.80 | ALDH1A1 (0.45) | MKNK1HTTPKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL3886733 | 0.79 | HDAC3 (0.45) | HDAC3HDAC1HDAC2SMN1; SMN2MEN1 | |
| SCHEMBL8326809 | 0.79 | SMN1; SMN2 (0.48) | MKNK1HDAC3HDAC1HDAC2PKM | |
| SCHEMBL1119617 | 0.79 | GNAI3 (0.51) | HTTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14514072 | 0.78 | SMN1; SMN2 (0.33) | HTTPOLBSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346588-A1 | IMIDAZOPYRIDINE AND OXAZOLOPYRIDINE DERIVATIVES AND ANALOGS THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF HIF-1/2A PATHWAY INHIBITION, AND INDUCTION OF FERROPTOSIS | KUDA THERAPEUTICS INC (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4531838-A1 | IMIDAZOPYRIDINE AND OXAZOLOPYRIDINE DERIVATIVES AND ANALOGS THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF HIF-1/2A PATHWAY INHIBITION, AND INDUCTION OF FERROPTOSIS | Kuda Therapeutics, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| EP-3663291-B1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS INC (US) | 2024-12-18 | — | — | EP | disclosed |
| WO-2023234970-A1 | IMIDAZOPYRIDINE AND OXAZOLOPYRIDINE DERIVATIVES AND ANALOGS THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF HIF-1/2A PATHWAY INHIBITION, AND INDUCTION OF FERROPTOSIS | KUDA Therapeutics, Inc. (US) | 2023-12-07 | — | — | WO | disclosed |
| US-11318120-B2 | Nuclear transport modulators and uses thereof | BIOGEN MA INC. (US) | 2022-05-03 | — | — | US | disclosed |
| US-20210251968-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | BIOGEN MA INC. (US) | 2021-08-19 | — | — | US | disclosed |
| US-10925859-B2 | Nuclear transport modulators and uses thereof | BIOGEN MA INC. (US) | 2021-02-23 | — | — | US | disclosed |
| US-10722497-B2 | Nuclear transport modulators and uses thereof | BIOGEN MA INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-20200230110-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | BIOGEN MA INC. (US) | 2020-07-23 | — | — | US | disclosed |
| EP-3663291-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | Biogen MA Inc. (US) | 2020-06-10 | — | — | EP | disclosed |
| WO-2013170068-A2 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS, INC. (US) | 2013-11-14 | — | — | WO | disclosed |
| CN-101023055-B | Cyclic amine derivative or salt thereof | ASTELLAS PHARMA INC | 2010-10-06 | — | — | CN | disclosed |
| WO-2009106753-A1 | NOVEL DERIVATIVES OF 1H-INDOL-1-YL UREA, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2009-09-03 | — | — | WO | disclosed |
| EP-2078716-A1 | New derivatives of 1H-indol-1-yl-urea, method for preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2009-07-15 | — | — | EP | disclosed |
| US-20090176794-A1 | 1H-INDOL-1-YL-UREA COMPOUNDS | LES LABORATOIRES SERVIER (FR) | 2009-07-09 | — | — | US | disclosed |
| US-7449462-B2 | Triazole derivatives which inhibit vasopressin antagonistic activity | PFIZER, INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20070203132-A1 | Triazole derivatives which inhibit vasopressin antagonistic activity | PFIZER INC | 2007-08-30 | — | — | US | disclosed |
| US-20070197594-A1 | Cyclic amine derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2007-08-23 | — | — | US | disclosed |
| CN-101023055-A | Cyclic amine derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2007-08-22 | — | — | CN | disclosed |
| EP-1795524-A1 | CYCLIC AMINE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2007-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210251968-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | XPO1, XPO5, XPOT | MKNK1 3315/4885HDAC3 195/4885HDAC1 279/4885 |
| US-20250346588-A1 | IMIDAZOPYRIDINE AND OXAZOLOPYRIDINE DERIVATIVES AND ANALOGS THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF HIF-1/2A PATHWAY INHIBITION, AND INDUCTION OF FERROPTOSIS | HIF1AN, HIF1A, EGLN2 | MKNK1 828/4885HDAC3 742/4885HDAC1 318/4885 |
| US-20070197594-A1 | Cyclic amine derivative or salt thereof | GRIN1, PARK7, GRIN3A | MKNK1 176/4885HDAC3 2053/4885HDAC1 118/4885 |
| US-10925859-B2 | Nuclear transport modulators and uses thereof | XPO1, XPO5, XPOT | MKNK1 2934/4885HDAC3 130/4885HDAC1 194/4885 |
| US-11318120-B2 | Nuclear transport modulators and uses thereof | XPO1, XPO5, XPOT | MKNK1 3315/4885HDAC3 195/4885HDAC1 279/4885 |
| US-20070203132-A1 | Triazole derivatives which inhibit vasopressin antagonistic activity | AVPR2, PRLHR, AVPR1A | MKNK1 1806/4885HDAC3 485/4885HDAC1 976/4885 |
| US-20200230110-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | XPO1, XPO5, XPOT | MKNK1 2934/4885HDAC3 130/4885HDAC1 194/4885 |
| US-10722497-B2 | Nuclear transport modulators and uses thereof | XPO1, XPO5, KPNB1 | MKNK1 3049/4885HDAC3 129/4885HDAC1 164/4885 |
| US-20090176794-A1 | 1H-INDOL-1-YL-UREA COMPOUNDS | TPH1, HTR1D, IDO1 | MKNK1 2593/4885HDAC3 1725/4885HDAC1 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.