Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11917942 | 0.92 | THRB (0.53) | THRBNPC1MAPTRAB9A | |
| SCHEMBL12742904 | 0.89 | KMT2A (0.44) | THRBNR4A2MAOBPARP10MEN1 | |
| SCHEMBL25796355 | 0.86 | THRB (0.65) | THRBMEN1KMT2ALSSGAA | |
| SCHEMBL14010348 | 0.86 | THRB (0.59) | THRBLMNANPC1MAPTRAB9A | |
| SCHEMBL12154154 | 0.85 | THRB (0.42) | THRBMAOB | |
| SCHEMBL1532888 | 0.85 | THRB (0.55) | THRBLSS | |
| SCHEMBL13289743 | 0.84 | THRB (0.46) | THRBMAOBPARP10MEN1KMT2A | |
| SCHEMBL12434531 | 0.84 | THRB (0.46) | THRBMEN1KMT2ALMNANPC1 | |
| SCHEMBL14010408 | 0.84 | THRB (0.46) | THRBPARP10NPC1MAPTRAB9A | |
| SCHEMBL12733792 | 0.84 | KMT2A (0.42) | THRBNR4A2MAOBPARP10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449223-B2 | containing an additive that improves the level of defects in the vicinity of the air interface for an optically anisotropic medium that exhibits either tilted alignment or horizontal alignment | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20070170394-A1 | Polymerizable liquid crystal composition and optically anisotropic medium | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-07-26 | — | — | US | disclosed |